AstraZeneca vs McDonald's: Founders, CEOs and History

Company facts

Founders

CEOs and their tenures

Timeline: AstraZeneca and McDonald's side by side

1. 1913AstraZeneca

   Astra AB Founded in Södertälje, Sweden

   400 doctors and apothecaries establish Astra AB to manufacture pharmaceuticals for the Swedish market, creating the foundation for what would become one of Europe's largest drug companies.

2. 1940McDonald's

   First McDonald's Opens in San Bernardino

   Richard and Maurice McDonald opened the first McDonald's restaurant on May 15, 1940 in San Bernardino, California. The original drive-in gave the brothers a live operating laboratory before they stripped the model down to a faster, lower-cost menu.

3. 1948McDonald's

   Speedee Service System Introduced

   The brothers simplified operations in 1948 around 15-cent hamburgers, shakes, and fries.

4. 1955McDonald's

   Ray Kroc Opens Des Plaines Restaurant

   Ray Kroc opened his first McDonald's in Des Plaines, Illinois on April 15, 1955 after becoming the brothers' franchise agent. That restaurant became the base for converting a California operating idea into a national franchise system.

5. 1961McDonald's

   Hamburger University Opens

   Hamburger University opened in the basement of an Elk Grove Village, Illinois restaurant in 1961. The training program mattered because it formalized the standards and operating routines that franchisees needed to deliver a consistent experience.

6. 1961McDonald's

   Kroc Buys the Brothers' Company

   McDonald's says it acquired the rights to the brothers' company in 1961 for $2.7 million. The deal gave Kroc control of the name and system, setting up the real estate-backed franchise model that later defined parent-company economics.

7. 1968McDonald's

   Big Mac Added to National Menu

   The Big Mac, developed by owner-operator Jim Delligatti of Pittsburgh, was added to the national menu in 1968. It became a durable core product and a recognizable signal of the company's ability to turn franchisee ideas into systemwide menu platforms.

8. 1975McDonald's

   Egg McMuffin Builds Breakfast

   The Egg McMuffin, created by owner-operator Herb Peterson of Santa Barbara, California, was added to the national menu in 1975. It helped turn breakfast into a major daypart rather than leaving the restaurants dependent on lunch and dinner traffic.

9. 1993AstraZeneca

   Zeneca Group Spun Off from ICI

   Imperial Chemical Industries demerges its pharmaceuticals and agrochemicals businesses to form Zeneca Group PLC, with initial products including Zestril, Nolvadex, and Zoladex generating approximately $3.2 billion in annual sales.

10. 1999AstraZeneca

    Astra and Zeneca Merge to Form AstraZeneca

    The all-share merger of equals completes on 6 April 1999, creating AstraZeneca PLC.

11. 2000AstraZeneca

    Nexium Launch Replaces Prilosec

    AstraZeneca launches Nexium (esomeprazole), the single-isomer successor to Losec/Prilosec, in Europe in 2000 and in the United States in 2001 after FDA approval on 20 February 2001.

12. 2003McDonald's

    I'm Lovin' It Campaign Launches

    McDonald's launched its global "I'm lovin' it" marketing campaign in 2003, its first worldwide brand campaign.

13. 2006AstraZeneca

    Acquisition of Cambridge Antibody Technology

    AstraZeneca agrees in May 2006 to buy Cambridge Antibody Technology for 1,320 pence a share, valuing the UK biotech at 702 million pounds or about $1.32 billion.

14. 2007AstraZeneca

    Acquisition of MedImmune for $15.6 Billion

    AstraZeneca acquires MedImmune for $15.6 billion, entering the biologics market and gaining the Synagis respiratory syncytial virus franchise and antibody technology platforms. The Gaithersburg facility becomes one of three global R&D centres.

15. 2012AstraZeneca

    Pascal Soriot Appointed CEO

    Pascal Soriot joins AstraZeneca as Chief Executive Officer on October 1, 2012, with a base salary of $1.4 million and a mandate to reverse declining revenue and R&D productivity through science-led investment.

16. 2014AstraZeneca

    Pfizer Hostile Takeover Rejected

    AstraZeneca's board rejects a $117 billion hostile takeover offer from Pfizer, with Soriot arguing that the undervaluation would destroy long-term shareholder value and pipeline potential.

17. 2014AstraZeneca

    Acquisition of Almirall Respiratory Portfolio

    AstraZeneca acquires the respiratory portfolio of Spanish pharmaceutical company Almirall for approximately $2.1 billion, strengthening the company's position in COPD and asthma with products including Eklira and pipeline candidates that become Breztri.

18. 2015AstraZeneca

    Tagrisso Approved for EGFR-Mutated Lung Cancer

    The FDA approves Tagrisso (osimertinib) in November 2015 for metastatic EGFR T790M mutation-positive non-small cell lung cancer, the first product from Soriot's reinvestment strategy to reach market.

19. 2017AstraZeneca

    Imfinzi Approved Based on PACIFIC Trial

    The FDA approves Imfinzi (durvalumab) for unresectable stage III non-small cell lung cancer after chemoradiation, based on PACIFIC trial data showing survival benefits.

20. 2017McDonald's

    Global McDelivery Day with UberEATS

    McDonald's marked Global McDelivery Day in 2017 to support the broader launch of McDelivery with UberEATS. Delivery expanded restaurant reach beyond the counter and drive-thru, while also adding packaging, marketplace-fee, and kitchen-throughput challenges.

21. 2019McDonald's

    Dynamic Yield Acquisition

    McDonald's agreed to acquire Dynamic Yield in 2019 to personalize drive-thru menu boards, kiosks, and app experiences using signals such as time of day, weather, restaurant traffic, and trending items.

22. 2020AstraZeneca

    COVID-19 Vaccine Development with Oxford University

    AstraZeneca partners with the University of Oxford to develop and manufacture the Vaxzevria COVID-19 vaccine, distributing billions of doses globally at nonprofit pricing during the pandemic peak.

23. 2021AstraZeneca

    Acquisition of Alexion Pharmaceuticals for $39 Billion

    AstraZeneca completes the $39 billion acquisition of Alexion on July 21, 2021, entering the rare disease market with Soliris and Ultomiris and creating a dedicated rare disease unit headquartered in Boston.

24. 2023AstraZeneca

    CinCor Pharma Acquired for up to $1.8 Billion

    AstraZeneca agrees on 9 January 2023 to acquire CinCor Pharma for up to $1.8 billion, $26 per share in cash plus a $10 per share contingent value right, to gain baxdrostat, an aldosterone synthase inhibitor for resistant hypertension.

25. 2024AstraZeneca

    Total Revenue Reaches $54.073 Billion

    AstraZeneca reports Total Revenue of $54.073 billion for fiscal year 2024, an 18% increase at actual rates and 21% at constant exchange rates, with 16 blockbuster medicines, 74 regulatory events, and 24 pipeline progression events.

26. 2024AstraZeneca

    Fusion Pharmaceuticals and Gracell Acquisitions

    AstraZeneca acquires Fusion Pharmaceuticals for $2 billion to access radiopharmaceutical technology and Gracell Biotechnologies for $1.2 billion for cell therapy manufacturing, expanding modality diversity into radiopharmaceuticals and CAR-T.

27. 2024McDonald's

    Quarter Pounder E. Coli Outbreak

    U.S. Public health agencies linked a 2024 E. Coli outbreak to slivered onions served on McDonald's Quarter Pounders in affected states.

28. 2025AstraZeneca

    Total Revenue Reaches $58.739 Billion

    AstraZeneca reports Total Revenue of $58.739 billion for fiscal year 2025, an 8% increase at constant exchange rates, with 16 positive Phase III readouts, 43 major market approvals, and a commitment to invest $50 billion in U.S. manufacturing by 2030.

29. 2025AstraZeneca

    EsoBiotec Acquired for Up to $1 Billion

    AstraZeneca acquires Belgian biotech EsoBiotec for up to $1 billion to access in vivo cell therapy technology, eliminating the need for ex vivo manufacturing in CAR-T therapies.

30. 2025AstraZeneca

    $50 Billion US Manufacturing and R&D Commitment

    AstraZeneca announces on 21 July 2025 that it will invest $50 billion in United States manufacturing and research by 2030, including a new Virginia facility later raised to $4.5 billion.

31. 2025McDonald's

    $26.9B FY2025 Revenue

    McDonald's reported $26.885 billion in FY2025 revenue and $8.563 billion in net income.

32. 2026AstraZeneca

    Ordinary Shares Begin Trading on the NYSE

    AstraZeneca ordinary shares start trading on the New York Stock Exchange on 2 February 2026 under the ticker AZN, after the American Depositary Share programme and certain debt securities stopped trading on Nasdaq on 30 January 2026.

33. 2026AstraZeneca

    Baxfendy Approved in the US for Hypertension

    The FDA approves Baxfendy (baxdrostat) in May 2026 as the first aldosterone synthase inhibitor for hypertension, used in combination with other antihypertensives in adults who are not adequately controlled.

34. 2026AstraZeneca

    $15 Billion China Investment Through 2030

    AstraZeneca announces on 29 January 2026 that it will invest $15 billion in China through 2030 to expand manufacturing and research, in a market that is its second largest and about 12% of revenue.

Acquisitions

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