AstraZeneca vs Hitachi: Founders, CEOs and History

Company facts

Founders

CEOs and their tenures

Timeline: AstraZeneca and Hitachi side by side

1. 1910Hitachi

   Founding and First Induction Motor

   Namihei Odaira establishes the machinery repair shop that becomes Hitachi, and develops Japan's first 5-horsepower induction motor, establishing the foundation for the company's dominance in electrical engineering.

2. 1913AstraZeneca

   Astra AB Founded in Södertälje, Sweden

   400 doctors and apothecaries establish Astra AB to manufacture pharmaceuticals for the Swedish market, creating the foundation for what would become one of Europe's largest drug companies.

3. 1932Hitachi

   Expansion into Railway Technology

   Hitachi begins manufacturing electric locomotives and rail signaling systems, establishing a deep, institutionalized relationship with the Japanese national railway network that would evolve into the modern Hitachi Rail division.

4. 1959Hitachi

   Entry into Computing and Electronics

   Hitachi develops its first electronic computer, the HITAC, marking the company's strategic entry into the information technology sector and laying the groundwork for its future digital systems business.

5. 1993AstraZeneca

   Zeneca Group Spun Off from ICI

   Imperial Chemical Industries demerges its pharmaceuticals and agrochemicals businesses to form Zeneca Group PLC, with initial products including Zestril, Nolvadex, and Zoladex generating approximately $3.2 billion in annual sales.

6. 1999AstraZeneca

   Astra and Zeneca Merge to Form AstraZeneca

   The all-share merger of equals completes on 6 April 1999, creating AstraZeneca PLC.

7. 2000AstraZeneca

   Nexium Launch Replaces Prilosec

   AstraZeneca launches Nexium (esomeprazole), the single-isomer successor to Losec/Prilosec, in Europe in 2000 and in the United States in 2001 after FDA approval on 20 February 2001.

8. 2006AstraZeneca

   Acquisition of Cambridge Antibody Technology

   AstraZeneca agrees in May 2006 to buy Cambridge Antibody Technology for 1,320 pence a share, valuing the UK biotech at 702 million pounds or about $1.32 billion.

9. 2007AstraZeneca

   Acquisition of MedImmune for $15.6 Billion

   AstraZeneca acquires MedImmune for $15.6 billion, entering the biologics market and gaining the Synagis respiratory syncytial virus franchise and antibody technology platforms. The Gaithersburg facility becomes one of three global R&D centres.

10. 2012AstraZeneca

    Pascal Soriot Appointed CEO

    Pascal Soriot joins AstraZeneca as Chief Executive Officer on October 1, 2012, with a base salary of $1.4 million and a mandate to reverse declining revenue and R&D productivity through science-led investment.

11. 2014AstraZeneca

    Pfizer Hostile Takeover Rejected

    AstraZeneca's board rejects a $117 billion hostile takeover offer from Pfizer, with Soriot arguing that the undervaluation would destroy long-term shareholder value and pipeline potential.

12. 2014AstraZeneca

    Acquisition of Almirall Respiratory Portfolio

    AstraZeneca acquires the respiratory portfolio of Spanish pharmaceutical company Almirall for approximately $2.1 billion, strengthening the company's position in COPD and asthma with products including Eklira and pipeline candidates that become Breztri.

13. 2015AstraZeneca

    Tagrisso Approved for EGFR-Mutated Lung Cancer

    The FDA approves Tagrisso (osimertinib) in November 2015 for metastatic EGFR T790M mutation-positive non-small cell lung cancer, the first product from Soriot's reinvestment strategy to reach market.

14. 2016Hitachi

    Toshiaki Higashihara becomes CEO

    Toshiaki Higashihara became CEO of Hitachi in 2016. Shifted Hitachi from a sprawling conglomerate toward infrastructure and digital businesses.

15. 2017AstraZeneca

    Imfinzi Approved Based on PACIFIC Trial

    The FDA approves Imfinzi (durvalumab) for unresectable stage III non-small cell lung cancer after chemoradiation, based on PACIFIC trial data showing survival benefits.

16. 2020AstraZeneca

    COVID-19 Vaccine Development with Oxford University

    AstraZeneca partners with the University of Oxford to develop and manufacture the Vaxzevria COVID-19 vaccine, distributing billions of doses globally at nonprofit pricing during the pandemic peak.

17. 2020Hitachi

    Acquisition of ABB's Power Grids Business

    Hitachi executes the $11 billion acquisition of ABB's Power Grids business, renaming it Hitachi Energy and instantly establishing the company as the global leader in HVDC transmission and grid infrastructure.

18. 2021AstraZeneca

    Acquisition of Alexion Pharmaceuticals for $39 Billion

    AstraZeneca completes the $39 billion acquisition of Alexion on July 21, 2021, entering the rare disease market with Soliris and Ultomiris and creating a dedicated rare disease unit headquartered in Boston.

19. 2021Hitachi

    Acquisition of GlobalLogic

    The company acquires the global digital engineering firm GlobalLogic for $9.6 billion, instantly establishing Hitachi as a top-tier provider of advanced software and product design services for the automotive and telecommunications sectors.

20. 2022Hitachi

    Hitachi Construction Machinery Stake Sale

    Hitachi sold a controlling stake in Hitachi Construction Machinery to Itochu and Japan Industrial Partners, part of its exit from cyclical listed subsidiaries.

21. 2023AstraZeneca

    CinCor Pharma Acquired for up to $1.8 Billion

    AstraZeneca agrees on 9 January 2023 to acquire CinCor Pharma for up to $1.8 billion, $26 per share in cash plus a $10 per share contingent value right, to gain baxdrostat, an aldosterone synthase inhibitor for resistant hypertension.

22. 2024AstraZeneca

    Total Revenue Reaches $54.073 Billion

    AstraZeneca reports Total Revenue of $54.073 billion for fiscal year 2024, an 18% increase at actual rates and 21% at constant exchange rates, with 16 blockbuster medicines, 74 regulatory events, and 24 pipeline progression events.

23. 2024AstraZeneca

    Fusion Pharmaceuticals and Gracell Acquisitions

    AstraZeneca acquires Fusion Pharmaceuticals for $2 billion to access radiopharmaceutical technology and Gracell Biotechnologies for $1.2 billion for cell therapy manufacturing, expanding modality diversity into radiopharmaceuticals and CAR-T.

24. 2024Hitachi

    Acquired Thales Ground Transportation Systems

    Hitachi acquired Thales Ground Transportation Systems. Hitachi Rail completed its ~$1.88 billion (EUR 1.66 billion) acquisition of Thales's Ground Transportation Systems business, its rail signalling division, expanding Hitachi Rail to 51 countries and shiftin…

25. 2025AstraZeneca

    Total Revenue Reaches $58.739 Billion

    AstraZeneca reports Total Revenue of $58.739 billion for fiscal year 2025, an 8% increase at constant exchange rates, with 16 positive Phase III readouts, 43 major market approvals, and a commitment to invest $50 billion in U.S. manufacturing by 2030.

26. 2025AstraZeneca

    EsoBiotec Acquired for Up to $1 Billion

    AstraZeneca acquires Belgian biotech EsoBiotec for up to $1 billion to access in vivo cell therapy technology, eliminating the need for ex vivo manufacturing in CAR-T therapies.

27. 2025AstraZeneca

    $50 Billion US Manufacturing and R&D Commitment

    AstraZeneca announces on 21 July 2025 that it will invest $50 billion in United States manufacturing and research by 2030, including a new Virginia facility later raised to $4.5 billion.

28. 2025Hitachi

    Toshiaki Tokunaga Becomes CEO

    Toshiaki Tokunaga became President and CEO on April 1, 2025, succeeding Keiji Kojima, who became Executive Chairman.

29. 2026AstraZeneca

    Ordinary Shares Begin Trading on the NYSE

    AstraZeneca ordinary shares start trading on the New York Stock Exchange on 2 February 2026 under the ticker AZN, after the American Depositary Share programme and certain debt securities stopped trading on Nasdaq on 30 January 2026.

30. 2026AstraZeneca

    Baxfendy Approved in the US for Hypertension

    The FDA approves Baxfendy (baxdrostat) in May 2026 as the first aldosterone synthase inhibitor for hypertension, used in combination with other antihypertensives in adults who are not adequately controlled.

31. 2026AstraZeneca

    $15 Billion China Investment Through 2030

    AstraZeneca announces on 29 January 2026 that it will invest $15 billion in China through 2030 to expand manufacturing and research, in a market that is its second largest and about 12% of revenue.

32. 2026Hitachi

    Record Results and Home Appliance Sale

    Hitachi reported record FY2025 profit in April 2026 and agreed to sell 80.1% of its home appliance business to Nojima for about $737 million (¥110 billion).

Acquisitions

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