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AstraZeneca vs Hitachi: Revenue, Profit and Business Model

AstraZeneca reported $58.7B of revenue in FY2025 and $10.2B of net income. Hitachi reported ~$70.9B of revenue in FY2026 and ~$5.4B of net income.

Latest financial snapshot

AstraZeneca

Latest revenue
$58.7B (FY2025)
Net income
$10.2B
Net margin
17.4%
Revenue growth
+11.0% a year, FY2016–FY2025

Hitachi

Latest revenue
~$70.9B (FY2026)
Net income
~$5.4B
Net margin
7.6%
Revenue growth
+0.8% a year, FY2022–FY2026

Financial summary

AstraZeneca

AstraZeneca's Total Revenue fell from $33.6 billion in 2011 to a trough of $22.1 billion in 2018 as Seroquel, Nexium and Crestor lost exclusivity. Under Pascal Soriot the company redirected spending into oncology and specialty medicines, and revenue then grew every year to $58.7 billion in 2025, with profit for the year of $10.2 billion and gross profit of $48.1 billion on cost of sales of $10.6 billion. R&D investment reached $14.2 billion in 2025, about a quarter of Total Revenue, and the $39 billion Alexion acquisition added a rare disease business the company did not have before 2021.

Hitachi

Hitachi posted a ~$5.27 billion (¥787.3 billion) net loss for fiscal 2008, then the largest ever by a Japanese manufacturer. Under Takashi Kawamura and Hiroaki Nakanishi it cut loss-making consumer businesses, and later leaders sold listed subsidiaries such as Hitachi Chemical (2020), Hitachi Metals (2023), and a controlling stake in Hitachi Construction Machinery (2022). Revenue dipped from ~$72.9 billion (¥10.88 trillion) in FY2022 to ~$65.2 billion (¥9.73 trillion) in FY2023 as those units left, then climbed back to ~$71 billion (¥10.59 trillion) in FY2025 on organic growth. FY2025 adjusted EBITA was a record ~$8.78 billion (¥1.31 trillion) (12.4% margin) and net income was ~$5.38 billion (¥802.3 billion), up about 30%. In Q1 FY2026 (April-June 2026) revenue rose 20% to ~$18.2 billion (¥2,709.6 billion), helped by currency, and management raised full-year guidance.

Revenue and profit by year

AstraZeneca

AstraZeneca revenue, net income, margin and growth by fiscal year
YearRevenueNet incomeMarginGrowthSource
FY2025$58.7B$10.2B17.4%+8.6%Source
FY2024$54.1B$7B13.0%+18.0%Source
FY2023$45.8B$6B13.0%+3.3%Source
FY2022$44.4B$3.3B7.4%+18.5%Source
FY2021$37.4B$115M0.3%+40.6%Source
FY2020$26.6B$3.1B11.8%+9.2%Source
FY2019$24.4B$1.2B5.0%+10.4%Source
FY2018$22.1B$2B9.3%-1.7%Source
FY2017$22.5B$2.9B12.8%-2.3%Source
FY2016$23B$3.4B14.8%—Source
Full AstraZeneca financials

Hitachi

Hitachi revenue, net income, margin and growth by fiscal year
YearRevenueNet incomeMarginGrowthSource
FY2026~$70.9B~$5.4B7.6%+8.2%Source
FY2025~$65.5B~$4.1B6.3%+0.6%Source
FY2024~$65.2B~$4B6.1%-10.6%Source
FY2023~$72.9B~$4.3B6.0%+6.0%Source
FY2022~$68.8B~$3.9B5.7%—Source
Full Hitachi financials

Where the revenue comes from

AstraZeneca

  • Product Sales~95%

    Product Sales were $55,573 million in 2025, up 9%, or about 95% of Total Revenue. This is the direct sale of AstraZeneca-manufactured prescription medicines to wholesalers, pharmacies, hospitals and government buyers. Oncology was the largest therapy area at roughly $25.6 billion of revenue, up 17%, followed by Cardiovascular, Renal and Metabolism, with Respiratory and Immunology and Rare Disease making up most of the balance.

  • Alliance Revenue~5%

    Alliance Revenue was $3,067 million in 2025, up 39%, or about 5% of Total Revenue. It is mostly AstraZeneca's share of profits on co-commercialised medicines, led by the Enhertu and datopotamab deruxtecan antibody-drug conjugates developed with Daiichi Sankyo, plus Tezspire with Amgen and Lynparza and Koselugo with Merck in certain markets.

  • Collaboration Revenue<1%

    Collaboration Revenue was $99 million in 2025, down 89% from $923 million in 2024, so less than 1% of Total Revenue. It covers upfront fees, milestone payments and royalties on out-licensed assets, and moves sharply year to year because it depends on when individual deals are signed.

Hitachi

  • Digital Systems & Services

    Reported sector

    Japanese IT systems for finance and government, GlobalLogic digital engineering, cloud and managed services, and Lumada solutions.

  • Energy

    Reported sector

    Hitachi Energy grid infrastructure, HVDC, transformers, and related service contracts.

  • Mobility

    Reported sector

    Hitachi Rail trains, signalling and train control (including former Thales GTS), and maintenance.

  • Connective Industries

    Reported sector

    Building systems, industrial products and systems, Hitachi High-Tech, and, until its sale, home appliances.

Business model and strategy

AstraZeneca

How it makes money

AstraZeneca discovers, develops and sells prescription medicines, and the economics turn on patent-protected pricing funded by heavy research spending. It invested $14.2 billion in research and development in 2025, about a quarter of Total Revenue, and reported gross profit of $48.1 billion on cost of sales of $10.6 billion.

Growth strategy

AstraZeneca's growth strategy relies on extending its existing cancer drugs into earlier stages of treatment, before the cancer spreads, which increases the number of patients who can be treated. The $39 billion acquisition of Alexion Pharmaceuticals in 2021 also took it into rare diseases, where drugs treat small patient populations, carry high prices and face little generic competition.

Competitive advantage

AstraZeneca's main advantage is the depth of its oncology portfolio and the Phase III evidence behind it. Tagrisso, Imfinzi, Enhertu, Lynparza and Calquence each rest on trials that changed treatment practice, and the company had more than 100 Phase III studies running at the end of 2025 after 16 positive Phase III readouts during the year.

AstraZeneca business model in full

Hitachi

How it makes money

Hitachi is a B2B infrastructure and IT company. It sells long-lived physical assets (transformers, HVDC converter stations, trains, signalling, elevators, semiconductor metrology tools) and then earns recurring service, maintenance, and software revenue on that installed base. Lumada is the umbrella for the data, AI, and digital services layered on top, and Hitachi reports Lumada as a growing share of total revenue.

Growth strategy

Hitachi grows by attaching software and services to its installed base and by reshaping its portfolio. It is expanding Hitachi Energy factory capacity for transformers and HVDC, integrating Thales GTS into Hitachi Rail, and scaling Lumada through GlobalLogic and AI partnerships.

Competitive advantage

Hitachi's edge is owning both the operational technology and the IT. Hitachi Energy (built on ABB's former Power Grids business) is one of a handful of suppliers able to deliver HVDC links and large power transformers at scale, Hitachi Rail became a top-tier signalling supplier after buying Thales GTS in 2024, and GlobalLogic plus Hitachi's Japanese IT business supply the software.

Hitachi business model in full

Questions about AstraZeneca vs Hitachi

Which company has higher revenue — AstraZeneca PLC or Hitachi, Ltd.?

AstraZeneca PLC reported $58.7B (FY2025), while Hitachi, Ltd. reported ~$70.9B (FY2026). By last reported revenue, Hitachi, Ltd. is the larger business, with AstraZeneca PLC reporting a smaller revenue base. Note: these are from different fiscal years and are not a direct like-for-like comparison.

What is the market cap of AstraZeneca PLC vs Hitachi, Ltd.?

AstraZeneca PLC's market capitalisation stands at $254.6B, while Hitachi, Ltd.'s is $157.8B. AstraZeneca PLC carries the higher market valuation, reflecting investors' expectations of its future earnings power relative to Hitachi, Ltd..

Which is more financially efficient — AstraZeneca PLC or Hitachi, Ltd.?

AstraZeneca PLC generates $611k / employee in revenue per employee, while Hitachi, Ltd. generates $246k / employee. AstraZeneca PLC shows higher revenue efficiency per headcount, though this reflects business model differences — capital-light software companies routinely outperform labour-intensive manufacturers on this metric.

How do AstraZeneca PLC and Hitachi, Ltd. make money?

AstraZeneca PLC and Hitachi, Ltd. generate revenue in fundamentally different ways. AstraZeneca PLC: AstraZeneca discovers, develops and sells prescription medicines, and the economics turn on patent-protected pricing funded by heavy research spending. Hitachi, Ltd.: Hitachi is a B2B infrastructure and IT company.

Which company is valued higher relative to revenue — AstraZeneca PLC or Hitachi, Ltd.?

On a price-to-sales (P/S) basis, AstraZeneca PLC trades at 4.3x P/S and Hitachi, Ltd. at 2.2x P/S. AstraZeneca PLC commands a higher revenue multiple, typically indicating that investors expect faster growth or higher future margins compared to Hitachi, Ltd.. A higher multiple is not inherently better — it may also signal that the stock is priced for perfection.

Is AstraZeneca PLC bigger than Hitachi, Ltd.?

By last reported revenue, Hitachi, Ltd. (~$70.9B (FY2026)) is the larger company compared to AstraZeneca PLC ($58.7B (FY2025)). Revenue scale is one dimension of size — market capitalisation, employee count, and geographic reach are also relevant depending on the context.

Figures come from each company's filings and the sources linked beside them. Amounts reported in another currency are shown in US dollars at an approximate rate and marked with ~. Back to the AstraZeneca vs Hitachi overview

Content is for informational purposes only. Not financial advice. Data sourced from SEC filings, annual reports, and public records. See our full disclaimer and methodology.