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Company History

Biogen History: Founding, Growth & Key Milestones

Founded 1978 in Geneva, Switzerland

When was Biogen founded?

Biogen was founded in 1978 in Geneva, Switzerland by Kenneth Murray, Phillip Sharp, Walter Gilbert, Charles Weissmann and Heinz Schaller, making it 48 years old.

Founded
1978
Founding place
Geneva, Switzerland
Founders
Kenneth Murray, Phillip Sharp, Walter Gilbert, Charles Weissmann and Heinz Schaller
Headquarters today
Cambridge, Massachusetts
Milestones documented
18 (1978–2026)
Current CEO
Christopher A. Viehbacher
Acquisitions
8
YearEvent
1978Biotechnology Geneva founded
1980Alpha interferon cloned
1983Initial public offering
1985James Vincent restructures the company
1996Avonex approved for multiple sclerosis
2003Merger with IDEC Pharmaceuticals
2004Tysabri approved, then withdrawn
2013Tecfidera launch and full Tysabri rights
2015Name returns to Biogen
2016Spinraza approved for SMA
2017Bioverativ spin-off
2020Tecfidera patent loss
2021Aduhelm accelerated approval
2022Christopher Viehbacher becomes CEO
2023Leqembi approval and Reata acquisition
2024Aduhelm discontinued, HI-Bio acquired
2025FY2025 revenue of $9.89 billion
2026Apellis acquisition and new dosing approvals
Where was Biogen founded?
Biogen was founded in Geneva, Switzerland in 1978. wikidata.org
Who founded Biogen?
Biogen was founded by Kenneth Murray, Phillip Sharp, Walter Gilbert, Charles Weissmann and Heinz Schaller.
When did Biogen start?
Biogen was founded in 1978.
How old is Biogen?
Biogen is 48 years old as of 2026.

Founding Story

Biogen began in 1978 as Biotechnology Geneva, set up in Switzerland by five academic molecular biologists: Walter Gilbert (Harvard), Phillip Sharp (MIT), Kenneth Murray (Edinburgh), Heinz Schaller (Heidelberg) and Charles Weissmann (Zurich). Weissmann's Zurich laboratory cloned human alpha interferon in 1980, and Murray and Schaller worked on producing hepatitis B antigens with recombinant DNA, work behind later hepatitis B vaccines. Gilbert, who won the 1980 Nobel Prize in Chemistry, left Harvard to run the company. Licensing those discoveries to larger drugmakers, rather than selling its own drugs, is what kept Biogen going through the 1980s.

Founders

Kenneth Murray

Murray co-founded Biogen in 1978. In Edinburgh he and his colleagues used genetic engineering to produce hepatitis B virus antigens in bacteria, work that led to one of the first recombinant vaccines and to diagnostic tests. Royalties from the hepatitis B technology helped sustain Biogen through the 1980s, and Murray used his own share to set up the Darwin Trust of Edinburgh, which funds young scientists. He was knighted in 1993 and died in April 2013. Education: University of Birmingham. (Exact birth year remains publicly undisclosed).

Phillip Sharp

Sharp was one of Biogen's 1978 founders and served on the company's board for many years. His work on how genes are split and spliced underpins much of later RNA-based drug development, a field in which Biogen became a leader through its antisense alliance with Ionis. In 2002 Sharp also co-founded Alnylam Pharmaceuticals, a developer of RNA interference medicines. Phillip Sharp was born in 1944 in Falmouth. Education: University of Illinois Urbana-Champaign; Union Commonwealth University.

Walter Gilbert

Gilbert helped found Biogen in 1978 and left his Harvard post to serve as its chief executive from 1981 to 1984, an unusual move for a Nobel laureate at the time. As research spending and losses mounted, the board asked him to step aside and he returned to academic work. He later became an early advocate of the Human Genome Project and in 1992 co-founded Myriad Genetics. Walter Gilbert was born in 1932 in Boston. Education: Trinity College; University of Cambridge.

Charles Weissmann

Weissmann co-founded Biogen in 1978. In 1980 his Zurich laboratory reported cloning human leukocyte (alpha) interferon and producing it in bacteria, Biogen's first major scientific result. The technology was licensed to Schering-Plough and became Intron A, an early source of royalties. Weissmann later became a leading prion researcher, showing that mice lacking the prion protein gene are resistant to scrapie. Weissmann was born on October 14, 1931 and died on December 11, 2025. A Hungarian-Swiss molecular biologist, he is known for the first cloning and expression of interferon and for work on the molecular genetics of prion diseases. (Exact birth year remains publicly undisclosed).

Heinz Schaller

Schaller co-founded Biogen in 1978 with Gilbert, Sharp, Murray and Weissmann. At Heidelberg he turned to hepatitis B virus research in the late 1970s, sequenced the viral genome with Gilbert and Murray and contributed to the recombinant DNA work behind a widely used hepatitis B vaccine. He co-founded Heidelberg's Center for Molecular Biology (ZMBH) in 1982, received the Robert Koch Medal in 2004, and with his wife Chica Schaller set up a foundation that funds young biomedical researchers. (Exact birth year remains publicly undisclosed).

Key Milestones

1978

Biotechnology Geneva founded

Walter Gilbert, Phillip Sharp, Kenneth Murray, Heinz Schaller and Charles Weissmann founded the company in Geneva, Switzerland as Biotechnology Geneva to turn recombinant DNA research into medicines.

Source: en.wikipedia.org
1980

Alpha interferon cloned

Charles Weissmann's Zurich laboratory cloned human alpha interferon and produced it in bacteria. The technology was licensed to Schering-Plough, which sold it as Intron A.

Source: en.wikipedia.org
1983

Initial public offering

Biogen listed its shares during the first wave of biotechnology IPOs and expanded research in Europe and the United States.

Source: companieshistory.com
1985

James Vincent restructures the company

With about $100 million of accumulated losses, Biogen hired James L. Vincent as CEO. He cut costs and relied on royalties from licensed interferon and hepatitis B technology.

Source: en.wikipedia.org
1996

Avonex approved for multiple sclerosis

The FDA approved Avonex (interferon beta-1a) for relapsing MS. It was Biogen's first drug sold under its own name and the start of its MS franchise.

Source: companieshistory.com
2003

Merger with IDEC Pharmaceuticals

Biogen merged with San Diego's IDEC Pharmaceuticals, maker of Rituxan with Genentech, in a deal valued at about $6.8 billion. The combined company took the name Biogen Idec.

Source: en.wikipedia.org
2004

Tysabri approved, then withdrawn

The FDA approved Tysabri (natalizumab) for MS in November 2004. It was withdrawn in February 2005 after cases of the brain infection PML and returned in 2006 with a risk-management program.

Source: en.wikipedia.org
2013

Tecfidera launch and full Tysabri rights

The FDA approved the oral MS drug Tecfidera in March 2013, and Biogen paid Elan $3.25 billion for full rights to Tysabri.

Source: en.wikipedia.org
2015

Name returns to Biogen

Biogen Idec shortened its name to Biogen in March 2015 to reflect its focus on neuroscience.

Source: en.wikipedia.org
2016

Spinraza approved for SMA

The FDA approved Spinraza (nusinersen), developed with Ionis, in December 2016 as the first treatment for spinal muscular atrophy. Its list price was $750,000 for the first year.

Source: en.wikipedia.org
2017

Bioverativ spin-off

Biogen spun off its hemophilia business as Bioverativ in February 2017 to concentrate on neuroscience. Sanofi bought Bioverativ in 2018 for $11.6 billion.

Source: en.wikipedia.org
2020

Tecfidera patent loss

A US court invalidated a key Tecfidera patent in a challenge brought by Mylan, opening the US market to generic dimethyl fumarate. Biogen's revenue fell from $13.44 billion in 2020 to $10.98 billion in 2021.

Source: stockanalysis.com
2021

Aduhelm accelerated approval

On June 7, 2021 the FDA granted accelerated approval to Aduhelm (aducanumab) for Alzheimer's disease despite mixed trial results. At $56,000 a year and with limited insurance coverage, the launch failed.

Source: en.wikipedia.org
2022

Christopher Viehbacher becomes CEO

Former Sanofi CEO Christopher Viehbacher took over from Michel Vounatsos on November 14, 2022. Earlier that year Biogen agreed to pay $900 million to settle a False Claims Act kickback suit.

Source: justice.gov
2023

Leqembi approval and Reata acquisition

Leqembi (lecanemab), partnered with Eisai, received full FDA approval in July 2023. In September Biogen completed its $7.3 billion acquisition of Reata, adding Skyclarys, the first approved Friedreich's ataxia drug.

Source: en.wikipedia.org
2024

Aduhelm discontinued, HI-Bio acquired

Biogen discontinued Aduhelm in January 2024 to redirect resources to Leqembi, and in July completed the acquisition of Human Immunology Biosciences for $1.15 billion upfront, adding the kidney disease antibody felzartamab.

Source: en.wikipedia.org
2025

FY2025 revenue of $9.89 billion

Revenue rose 2.2% to $9.89 billion, with growth products reaching $3.3 billion and free cash flow of $2.1 billion. Biogen also announced a $2 billion investment in its Research Triangle Park manufacturing sites.

Source: sec.gov
2026

Apellis acquisition and new dosing approvals

The FDA approved a high-dose Spinraza regimen in March. Biogen completed its roughly $5.6 billion purchase of Apellis on May 14, and in July the FDA approved the Leqembi Iqlik autoinjector for starting treatment.

Source: biospace.com

Major Acquisitions

IDEC Pharmaceuticals

2003

An all-stock merger valued at about $6.8 billion that combined Biogen's MS business with IDEC's oncology and immunology products, including Rituxan, marketed with Genentech.

Fumapharm AG

2006

Bought the Swiss maker of the psoriasis drug Fumaderm and the oral fumarate BG-12, then being studied in multiple sclerosis.

Elan (Tysabri rights)

2013

Paid Elan $3.25 billion for full ownership of Tysabri, which the two companies had shared.

Nightstar Therapeutics

2019

Acquired the UK gene therapy company for $25.50 per share to build a pipeline for inherited retinal disorders.

Reata Pharmaceuticals

2023

Bought Reata for $172.50 per share in cash to obtain Skyclarys, the first approved treatment for Friedreich's ataxia.

Human Immunology Biosciences (HI-Bio)

2024

Paid $1.15 billion upfront, with up to $650 million in milestones, for felzartamab, an anti-CD38 antibody for immune-mediated kidney and transplant diseases.

Alcyone Therapeutics

2025

Acquired a developer of implantable devices for delivering antisense drugs into the spinal fluid.

Apellis Pharmaceuticals

2026

Paid $41 per share in cash plus a contingent value right of up to $4 per share for Apellis, maker of Syfovre and Empaveli, completed May 14, 2026.

Keep researching Biogen

Biogen Company History FAQ

When and where was Biogen founded?

Biogen was founded in 1978 in Geneva, Switzerland as Biotechnology Geneva by five molecular biologists, including future Nobel laureates Walter Gilbert and Phillip Sharp. It later moved its headquarters to Cambridge, Massachusetts.

What was Biogen's first drug?

Avonex (interferon beta-1a), approved by the FDA in 1996 for relapsing multiple sclerosis, was the first drug Biogen sold under its own name. Before that it lived mainly on royalties from interferon and hepatitis B technology licensed to other companies.

What was Biogen Idec?

Biogen Idec was the name of the company formed when Biogen merged with San Diego's IDEC Pharmaceuticals in 2003. It returned to the name Biogen in March 2015.

Why was Tysabri withdrawn in 2005?

Tysabri was approved for MS in November 2004 but withdrawn in February 2005 after patients developed PML, a rare brain infection. It returned in 2006 with a risk-management program and remains one of Biogen's largest products.

Why did Biogen's revenue fall after 2019?

Revenue peaked at $14.38 billion in 2019. After a US court invalidated a key Tecfidera patent in 2020, generic competition drove revenue down to $9.84 billion by 2023. It was $9.89 billion in 2025.

What happened to Aduhelm?

Aduhelm received accelerated FDA approval for Alzheimer's disease in June 2021, but mixed trial data, a $56,000 launch price and Medicare's decision to cover it only in trials meant very few patients used it. Biogen discontinued it in January 2024.

What are Biogen's most recent milestones?

In 2026 the FDA approved a high-dose Spinraza regimen (March) and the Leqembi Iqlik autoinjector for starting Alzheimer's treatment (July), and Biogen completed its roughly $5.6 billion acquisition of Apellis on May 14.

When was Biogen founded?

Biogen was founded in 1977 in Geneva, Switzerland, by a "dream team" of renowned biologists, including Nobel Laureates Walter Gilbert and Phillip Sharp.

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