Pfizer vs TotalEnergies: Founders, CEOs and History
Pfizer was founded in 1849 by Charles Pfizer, Charles Erhart and is led by Albert Bourla. TotalEnergies was founded in 1924 by Raymond Poincaré, Ernest Mercier and is led by Patrick Pouyanné.
Company facts
Pfizer
- Founded
- 1849
- Headquarters
- New York, New York
- Current CEO
- Albert Bourla
- Employees
- 75,000
TotalEnergies
- Founded
- 1924
- Headquarters
- Paris, France
- Current CEO
- Patrick Pouyanné
- Employees
- 100,000
Founders
Pfizer
Charles Pfizer
Pfizer possesses a historic, immigrant founding story, rooted entirely in the rapid industrial expansion of 19th-century Brooklyn and defined by an effective, intensely meticulous German chemist and his ambitious confectioner cousin.
Charles Erhart
Charles Erhart's role in Pfizer's founding is less celebrated than his cousin's, partly because the company carries Charles Pfizer's name and partly because his commercial contributions were less visible than the scientific achievements that drove the company'…
TotalEnergies
Raymond Poincaré
Raymond Poincaré was President of France during World War I and Prime Minister when his government pushed for a national oil company in 1924.
Ernest Mercier
Ernest Mercier was the industrialist chosen to set up and chair Compagnie Française des Pétroles.
CEOs and their tenures
Pfizer
- Ian Read2010–2018
Chief Executive Officer
He ruthlessly cut R&D spending and eliminated tens of thousands of jobs, significantly boosting short-term earnings per share despite massive patent cliffs for blockbuster drugs like Lipitor.
Source - Albert Bourla2019–present
Chairman and Chief Executive Officer
A veterinarian by training who joined Pfizer Animal Health in 1993, Bourla became CEO on January 1, 2019 and Chairman in 2020.
Source - Dave Denton2022–2026
Chief Financial Officer
As CFO, he aggressively restructured the balance sheet following the Seagen acquisition, prioritizing debt reduction while defending the dividend.
Source - Chris Boshoff2025–present
Chief Scientific Officer and President, Research & Development
He completely restructured the research and development organization to focus on antibody-drug conjugates (ADCs), aggressively expanding Pfizer's pipeline of cancer therapeutics.
Source - Cecile Guegan2026–present
Interim Chief Financial Officer
She modernized the company's internal auditing and compliance structures, ensuring rapid but safe clinical execution for high-priority vaccine programs.
Source
TotalEnergies
- Thierry Desmarest1995–2007
Chairman and Chief Executive Officer
Under his leadership, Total more than doubled in size, becoming a dominant global supermajor capable of competing with Exxon and Shell.
Source - Christophe de Margerie2007–2014
Chairman and Chief Executive Officer
He transformed Total into one of the most geographically diverse supermajors before his sudden death in a plane crash in 2014.
Source - Patrick Pouyanné2014–present
Chairman and Chief Executive Officer
CEO since October 2014 and Chairman since December 2015, Pouyanné renamed the company TotalEnergies in 2021, expanded LNG and Integrated Power, and kept returns at the top of the majors (12.6% ROACE in 2025).
Source - Jean-Pierre Sbraire2019–present
Chief Financial Officer
As CFO, he fortified the balance sheet during unprecedented energy market volatility following the geopolitical shocks of 2022.
Source
Timeline: Pfizer and TotalEnergies side by side
1849Pfizer
Pfizer Founded
Charles Pfizer and Charles Erhart founded the company in Brooklyn.
1924TotalEnergies
Compagnie Francaise des Petroles founded
The French state-backed oil company was created to secure access to petroleum resources and became the predecessor of TotalEnergies.
1944Pfizer
Penicillin Scale-Up
Pfizer helped industrialize penicillin production during World War II.
1954TotalEnergies
Total Brand Created
The company created the Total brand in 1954 to build a retail distribution network.
1995TotalEnergies
Thierry Desmarest becomes CEO
Thierry Desmarest became CEO of TotalEnergies in 1995. Led Total from 1995 to 2007 and engineered the Petrofina and Elf Aquitaine combinations; remained Chairman until 2010.
1998Pfizer
Viagra Approved
The FDA approved Viagra in 1998.
1999TotalEnergies
Petrofina acquired; Elf Aquitaine follows in 2000
Total combined with Belgium's Petrofina in 1999 and Elf Aquitaine in 2000, operating as TotalFinaElf before reverting to Total in 2003.
2000Pfizer
Warner-Lambert Deal
Pfizer acquired Warner-Lambert, adding Lipitor.
2000TotalEnergies
Elf Aquitaine Acquired
Total acquired Elf Aquitaine in 2000, forming TotalFinaElf.
2007TotalEnergies
Christophe de Margerie becomes CEO
Christophe de Margerie became CEO of TotalEnergies in 2007. CEO from 2007 and Chairman from 2010 until his death in a plane accident at Moscow's Vnukovo airport in October 2014.
2011TotalEnergies
Acquired SunPower (majority stake)
TotalEnergies acquired SunPower (majority stake).
2018TotalEnergies
Direct Energie acquired
Total bought French power and gas retailer Direct Energie, the base of its European retail electricity business.
2019Pfizer
Albert Bourla becomes CEO
Albert Bourla became CEO of Pfizer in 2019. A veterinarian by training who joined Pfizer Animal Health in 1993, Bourla became CEO on January 1, 2019 and Chairman in 2020.
2020Pfizer
BioNTech COVID Vaccine Partnership
Pfizer and BioNTech brought Comirnaty through emergency authorization.
2021TotalEnergies
Total becomes TotalEnergies
The company changed its name to TotalEnergies to reflect a broader multi-energy strategy spanning oil, gas, electricity, renewables, and low-carbon energy.
2023Pfizer
Seagen Acquisition
Pfizer completed the $43 billion Seagen acquisition.
2025Pfizer
Chris Boshoff Becomes CSO
Chris Boshoff became Chief Scientific Officer and President, Research & Development effective January 1, 2025.
2025Pfizer
Metsera Acquisition
Pfizer completed its acquisition of obesity drug developer Metsera in November 2025 for up to about $10 billion including CVRs.
2025Pfizer
FY2025 Revenue Base
Pfizer reported $62.579 billion of FY2025 revenue.
2025TotalEnergies
2025 results
Revenues from sales of $182.344 billion, adjusted net income of $15.6 billion (down 15%), IFRS net income of $13.127 billion and a €3.40 dividend.
2026Pfizer
Innovent Oncology Collaboration
Pfizer signed a 12-program cancer collaboration with Innovent Biologics: $650 million upfront and up to $9.85 billion in milestones.
2026TotalEnergies
Mozambique LNG full restart
On January 29, 2026, Patrick Pouyanné and President Daniel Chapo announced the full restart of the roughly $20 billion Mozambique LNG project after force majeure was lifted in November 2025.
2026TotalEnergies
Q2 2026 results
Adjusted net income of $6.0 billion and cash flow of $9.8 billion in the second quarter as higher oil prices tied to the Middle East conflict lifted earnings.
Acquisitions
Pfizer
- Metsera, Inc.2025$7B
- Seagen Inc.2023$43B
- Medivation Inc.2016$14B
- Wyeth2009$68B
- Pharmacia Corporation2003$60B
- Warner-Lambert Company2000$111B
TotalEnergies
- Direct Energie2018$1.6B
- Saft Groupe2016Undisclosed
- SunPower (majority stake)2011Undisclosed
- Petrofina and Elf Aquitaine1999Undisclosed
Questions about Pfizer vs TotalEnergies
Who is the CEO of Pfizer Inc. and TotalEnergies SE?
Pfizer Inc. is led by Albert Bourla and TotalEnergies SE is led by Patrick Pouyanné. Both serve as the top executive responsible for the company's strategy, operations, and financial performance.
When was Pfizer Inc. founded vs TotalEnergies SE?
Pfizer Inc. was founded in 1849 — 75 years before TotalEnergies SE, which was founded in 1924. Pfizer Inc.'s longer operating history gives it a deeper track record but also potentially more institutional inertia compared to the younger TotalEnergies SE.
How many employees does Pfizer Inc. have compared to TotalEnergies SE?
Pfizer Inc. employs approximately 75,000 people, while TotalEnergies SE employs approximately 100,000. TotalEnergies SE has the larger workforce at 100,000 employees, compared to Pfizer Inc.'s 75,000. A higher headcount does not necessarily imply greater efficiency — it often reflects differences in business model (e.g., manufacturing vs. software).
Where are Pfizer Inc. and TotalEnergies SE headquartered?
Pfizer Inc. is headquartered in United States and TotalEnergies SE is headquartered in France. Their different home markets mean they may face different regulatory frameworks, tax regimes, and currency exposure.
Who founded Pfizer Inc. and TotalEnergies SE?
Pfizer Inc. was founded by Charles Pfizer, Charles Erhart. TotalEnergies SE was founded by Raymond Poincaré, Ernest Mercier.
Which company has a longer operating history — Pfizer Inc. or TotalEnergies SE?
Pfizer Inc. has been operating for approximately 177 years, making it the more established of the two companies. TotalEnergies SE has been in operation for around 102 years. A longer operating history often signals greater institutional resilience and brand recognition, though it can also mean slower adaptation to new market conditions.
Figures come from each company's filings and the sources linked beside them. Amounts reported in another currency are shown in US dollars at an approximate rate and marked with ~. Back to the Pfizer vs TotalEnergies overview