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American Express vs Johnson & Johnson: Revenue, Profit and Business Model

American Express reported $72.2B of revenue in FY2025 and $10.8B of net income. Johnson & Johnson reported $94.2B of revenue in FY2025 and $26.8B of net income.

Latest financial snapshot

American Express

Latest revenue
$72.2B (FY2025)
Net income
$10.8B
Net margin
15.0%
Revenue growth
+8.2% a year, FY2016–FY2025

Johnson & Johnson

Latest revenue
$94.2B (FY2025)
Net income
$26.8B
Net margin
28.5%
Revenue growth
+3.0% a year, FY2016–FY2025

Financial summary

American Express

American Express reported $72.2 billion in total revenues net of interest expense for FY2025, up 10 percent, and $10.8 billion of net income, or $15.38 per diluted share. The mix is less fee-only than its premium image suggests: discount revenue on merchant transactions was $37.4 billion, net interest income on card member loans was $17.4 billion, net card fees were $10.0 billion and service fees and other revenue were $7.5 billion. Growth in 2025 came disproportionately from the two smaller lines, with net card fees up 18 percent and net interest income up 12 percent against 6 percent growth in discount revenue. Return on average equity was 33.9 percent, the net write-off rate on consumer and small business loans and receivables was 2.0 percent, and the company declared $3.28 per share in dividends while average diluted shares fell from 713 million to 696 million.

Johnson & Johnson

J&J's sales grew from $85.2 billion in 2023 to $88.8 billion in 2024 and $94.2 billion in 2025, while FY2025 net earnings reached $26.8 billion. Q2 2026 sales were $25.31 billion (Innovative Medicine $16.38 billion, MedTech $8.93 billion), net earnings were $5.53 billion, adjusted EPS was $2.90, and first-half free cash flow was about $8.7 billion. Management guides 2026 sales of $100.8 to $101.4 billion and adjusted EPS of $11.60 to $11.75. The company has raised its dividend for more than 60 consecutive years, and its market value was roughly $644 billion in mid-September 2026.

Revenue and profit by year

American Express

American Express revenue, net income, margin and growth by fiscal year
YearRevenueNet incomeMarginGrowthSource
FY2025$72.2B$10.8B15.0%+9.5%Source
FY2024$65.9B$10.1B15.4%+9.0%Source
FY2023$60.5B$8.4B13.8%+14.5%Source
FY2022$52.9B$7.5B14.2%+24.7%Source
FY2021$42.4B$8.1B19.0%+17.4%Source
FY2020$36.1B$3.1B8.7%-17.1%Source
FY2019$43.6B$6.8B15.5%+8.0%Source
FY2018$40.3B$6.9B17.2%+9.4%Source
FY2017$36.9B$2.7B7.5%+4.1%Source
FY2016$35.4B$5.4B15.2%—Source
Full American Express financials

Johnson & Johnson

Johnson & Johnson revenue, net income, margin and growth by fiscal year
YearRevenueNet incomeMarginGrowthSource
FY2025$94.2B$26.8B28.5%+6.0%Source
FY2024$88.8B$14.1B15.8%+4.3%Source
FY2023$85.2B$35.2B41.3%+6.5%Source
FY2022$80B$17.9B22.4%+1.6%Source
FY2021$78.7B$20.9B26.5%-4.7%Source
FY2020$82.6B$14.7B17.8%+0.6%Source
FY2019$82.1B$15.1B18.4%+0.6%Source
FY2018$81.6B$15.3B18.8%+6.7%Source
FY2017$76.5B$1.3B1.7%+6.3%Source
FY2016$71.9B$16.5B23.0%—Source
Full Johnson & Johnson financials

Where the revenue comes from

American Express

  • Discount Revenue (Merchant Fees)~52%

    Discount revenue is the fee American Express charges merchants on card transactions. It was $37,401 million in FY2025, up 6 percent, and equalled 2.24 percent of billed business. It remains the largest revenue line and moves with billed business, merchant mix and geography.

  • Net Interest Income~24%

    Net interest income is earned on card member loans and receivables after funding costs. It was $17,364 million in FY2025, up 12 percent, on a net interest yield of 8.1 percent, helped by growth in revolving balances and by lending features added to charge card products.

  • Net Card Fees~14%

    Net card fees are the annual fees on consumer, small business and corporate cards. They reached $9,993 million in FY2025, up 18 percent, at an average of $117 per proprietary card in force, driven by new acquisitions on fee-paying products and by the 2025 Platinum refresh.

  • Service Fees and Other Revenue~10%

    Service fees and other revenue was $7,471 million in FY2025, up 10 percent. It covers network partnership revenue from cards issued by partner banks, foreign currency fees on cross-currency spending, loyalty coalition and merchant service fees, delinquency fees, travel commissions and income from equity method investments.

Johnson & Johnson

  • Innovative Medicine~64%

    Innovative Medicine generated $60.401 billion in FY2025 sales across oncology, immunology, neuroscience, pulmonary hypertension, infectious disease, and cardiovascular/metabolism.

  • MedTech~36%

    MedTech generated $33.792 billion in FY2025 sales across surgery, orthopaedics, cardiovascular, and vision products.

Business model and strategy

American Express

How it makes money

American Express runs a closed-loop payments business: it issues the card, owns the network, underwrites the credit and contracts with the merchant. Visa and Mastercard only move the transaction between an issuing bank and an acquiring bank, so they never see both sides of a purchase.

Growth strategy

Amex's growth strategy is aggressively focused on capturing the next generation of wealthy spenders: Millennials and Gen Z. They have successfully revamped their well-known Platinum and Gold cards with perks tailored specifically for younger demographics (like Uber credits and dining rewards), resulting in rapid growth among younger cohorts.

Competitive advantage

American Express competes on the spending power of its card members rather than on price or ubiquity. Average spending per proprietary basic card member was $25,453 in 2025, which is the argument it makes to merchants who pay a higher discount rate, an average of 2.24 percent of billed business.

American Express business model in full

Johnson & Johnson

How it makes money

J&J makes money in two ways. Innovative Medicine (about 64% of FY2025 sales, $60.4 billion) sells patented prescription medicines to wholesalers, specialty pharmacies, hospitals, and governments; key products include DARZALEX for multiple myeloma, TREMFYA and STELARA in immunology, ERLEADA in prostate cancer, CARVYKTI cell therapy, and CAPLYTA, added through the 2025 Intra-Cellular Therapies deal.

Growth strategy

J&J is narrowing its portfolio toward higher-growth areas. It spun off consumer health as Kenvue in 2023, announced in October 2025 that it will separate its orthopaedics business as DePuy Synthes, and used acquisitions to refill its pipeline: Abiomed ($16.6 billion, 2022), Shockwave Medical ($13.1 billion, 2024), and Intra-Cellular Therapies ($14.6 billion, 2025).

Competitive advantage

J&J's edge is breadth plus balance-sheet strength. It runs one of the largest pharmaceutical R&D budgets in the industry, holds a AAA credit rating from S&P (one of only two US companies with that rating, alongside Microsoft), and sells into hospitals across pharmaceuticals and devices at the same time.

Johnson & Johnson business model in full

Questions about American Express vs Johnson & Johnson

Which company has higher revenue — American Express Company or Johnson & Johnson?

American Express Company reported $72.2B (FY2025), while Johnson & Johnson reported $94.2B (FY2025). By last reported revenue, Johnson & Johnson is the larger business, with American Express Company reporting a smaller revenue base.

What is the market cap of American Express Company vs Johnson & Johnson?

American Express Company's market capitalisation stands at $205.8B, while Johnson & Johnson's is $643.9B. Johnson & Johnson carries the higher market valuation, reflecting investors' expectations of its future earnings power relative to American Express Company.

Which is more financially efficient — American Express Company or Johnson & Johnson?

American Express Company generates $940k / employee in revenue per employee, while Johnson & Johnson generates $669k / employee. American Express Company shows higher revenue efficiency per headcount, though this reflects business model differences — capital-light software companies routinely outperform labour-intensive manufacturers on this metric.

How do American Express Company and Johnson & Johnson make money?

American Express Company and Johnson & Johnson generate revenue in fundamentally different ways. American Express Company: American Express runs a closed-loop payments business: it issues the card, owns the network, underwrites the credit and contracts with the merchant. Johnson & Johnson: J&J makes money in two ways.

Which company is valued higher relative to revenue — American Express Company or Johnson & Johnson?

On a price-to-sales (P/S) basis, American Express Company trades at 2.8x P/S and Johnson & Johnson at 6.8x P/S. Johnson & Johnson commands a higher revenue multiple, typically indicating that investors expect faster growth or higher future margins compared to American Express Company. A higher multiple is not inherently better — it may also signal that the stock is priced for perfection.

Is American Express Company bigger than Johnson & Johnson?

By last reported revenue, Johnson & Johnson ($94.2B (FY2025)) is the larger company compared to American Express Company ($72.2B (FY2025)). Revenue scale is one dimension of size — market capitalisation, employee count, and geographic reach are also relevant depending on the context.

Figures come from each company's filings and the sources linked beside them. Amounts reported in another currency are shown in US dollars at an approximate rate and marked with ~. Back to the American Express vs Johnson & Johnson overview

Content is for informational purposes only. Not financial advice. Data sourced from SEC filings, annual reports, and public records. See our full disclaimer and methodology.