Skip to main content

F. Hoffmann-La Roche AG

Company History

Roche History: Founding, Growth & Key Milestones

Founded 1896 in Basel, Switzerland

When was Roche founded?

Roche was founded in 1896 in Basel, Switzerland by Fritz Hoffmann-La Roche, making it 130 years old.

Founded
1896
Founding place
Basel, Switzerland
Founders
Fritz Hoffmann-La Roche
Headquarters today
Basel, Switzerland
Milestones documented
12 (1896–2025)
Current CEO
Thomas Schinecker
Acquisitions
10
YearEvent
1896F. Hoffmann-La Roche Founded in Basel
1898Commercial Breakthrough with Sirolin
1934First Industrial Synthesis of Vitamin C
1963Launch of Valium (Diazepam)
1968Establishment of Roche Diagnostics
1990Majority Stake in Genentech
1997Boehringer Mannheim Acquired
2008Severin Schwan becomes CEO
2009Full Acquisition of Genentech for $46.8 Billion
2018Foundation Medicine & Flatiron Health Acquisitions
2023Acquired Telavant
2025Group Sales Reach CHF 61.5 Billion
Where was Roche founded?
Roche was founded in Basel, Switzerland in 1896. wikidata.org
Who founded Roche?
Roche was founded by Fritz Hoffmann-La Roche.
When did Roche start?
Roche was founded in 1896.
How old is Roche?
Roche is 130 years old as of 2026.

Founding Story

Fritz Hoffmann-La Roche founded the company in Basel in 1896 to produce standardized medicines on an industrial scale. Early successes such as the cough syrup Sirolin funded foreign expansion. Roche later became a major vitamin producer after acquiring rights to Tadeus Reichstein's vitamin C synthesis in the 1930s, and benzodiazepines Librium (1960) and Valium (1963) made it one of the most profitable drugmakers of the post-war era.

Founders

Fritz Hoffmann-La Roche

Fritz Hoffmann-La Roche (1868-1920) founded F. Hoffmann-La Roche & Co. in Basel on 1 October 1896, at age 28. His idea was to manufacture standardized, branded medicines industrially and sell them internationally rather than rely on pharmacist-compounded remedies. Early products included the thyroid preparation Thyreoglandol, the cough syrup Sirolin and the digitalis extract Digalen. He opened foreign subsidiaries within a few years of founding, giving Roche an international footprint long before most competitors. Friedrich "Fritz" Hoffmann-La Roche was born on October 24, 1868 and died on April 18, 1920. Fritz Hoffmann-La Roche was born in 1868.

Key Milestones

1896

F. Hoffmann-La Roche Founded in Basel

Fritz Hoffmann-La Roche founds the enterprise in Basel, Switzerland, pioneering mass-manufactured, chemically standardized prescription pharmaceuticals.

Source: en.wikipedia.org
1898

Commercial Breakthrough with Sirolin

Roche launches non-prescription cough syrup Sirolin, achieving widespread international distribution and financing early clinical laboratories.

Source: en.wikipedia.org
1934

First Industrial Synthesis of Vitamin C

Roche becomes the first company to mass-produce synthetic Vitamin C (Redoxon) at industrial scale, anchoring decades of high-margin global cash flow.

Source: en.wikipedia.org
1963

Launch of Valium (Diazepam)

Roche introduces Valium, which becomes the world's most widely prescribed psychotropic medication and establishes global pharmaceutical leadership.

Source: en.wikipedia.org
1968

Establishment of Roche Diagnostics

Roche launches its dedicated diagnostic division, laying the foundation to become the world's preeminent in-vitro diagnostics (IVD) provider.

Source: en.wikipedia.org
1990

Majority Stake in Genentech

Roche bought a majority stake in Genentech in 1990.

Source: en.wikipedia.org
1997

Boehringer Mannheim Acquired

Roche bought Corange, the parent of Boehringer Mannheim, in 1997 for about $11 billion.

Source: en.wikipedia.org
2008

Severin Schwan becomes CEO

Severin Schwan became CEO of F. Hoffmann-La Roche in 2008. Led Roche for 14 years; handed over to Thomas Schinecker in March 2023 and became chairman.

Source: biopharmadive.com
2009

Full Acquisition of Genentech for $46.8 Billion

Roche completes its historic $46.8 billion buyout of American biotechnology pioneer Genentech, securing market leadership in oncology biologics.

Source: en.wikipedia.org
2018

Foundation Medicine & Flatiron Health Acquisitions

Roche acquires Foundation Medicine and Flatiron Health, integrating real-world oncology data analytics and genomic profiling into personalized healthcare.

Source: en.wikipedia.org
2023

Acquired Telavant

F. Hoffmann-La Roche acquired Telavant for $7.1 billion. Roche paid $7.1 billion upfront for Telavant to gain US and Japan rights to the anti-TL1A antibody RVT-3101 (afimkibart) for inflammatory bowel disease.

Source: roche.com
2025

Group Sales Reach CHF 61.5 Billion

Under CEO Thomas Schinecker, Roche delivers group sales of ~$73.8 billion (CHF 61.5 billion), driven by ~$57.2B (CHF 47.7B) in Pharmaceuticals and ~$16.6B (CHF 13.8B) in Diagnostics.

Source: roche.com

Major Acquisitions

Biomedical Reference Laboratories

1982

F. Hoffmann-La Roche acquired Biomedical Reference Laboratories in 1982 for $164 million.

Genentech

2009

Roche bought the roughly 44% of Genentech it did not already own for about $46.8 billion, after holding a majority stake since 1990.

Bina Technologies

2014

F. Hoffmann-La Roche acquired Bina Technologies in 2014.

Adheron Therapeutics

2015

F. Hoffmann-La Roche acquired Adheron Therapeutics in 2015 for $105 million.

ForSight VISION4

2017

F. Hoffmann-La Roche acquired ForSight VISION4 in 2017.

Foundation Medicine

2018

Roche bought the remaining shares of Foundation Medicine it did not own, in a deal valued at about $2.4 billion, to add comprehensive genomic profiling.

Telavant

2023

Roche paid $7.1 billion upfront for Telavant to gain US and Japan rights to the anti-TL1A antibody RVT-3101 (afimkibart) for inflammatory bowel disease.

Carmot Therapeutics

2023

Roche paid $2.7 billion upfront for Carmot to enter obesity, adding the incretin candidate CT-388 (enicepatide).

89bio

2025

Roche agreed in September 2025 to buy 89bio for $14.50 per share in cash plus a CVR of up to $6.00 per share, a total of up to about $3.5 billion, adding the MASH candidate pegozafermin.

PathAI

2026

Roche agreed in May 2026 to acquire Boston-based PathAI for $750 million upfront plus up to $300 million in milestones to strengthen AI-driven digital pathology.

Keep researching Roche

Roche Company History FAQ

When and where was Roche founded?

F. Hoffmann-La Roche & Co. was founded on October 1, 1896, in Basel, Switzerland, by entrepreneur Fritz Hoffmann-La Roche.

What was Roche's original commercial breakthrough product?

In 1898, Roche launched "Sirolin," a non-prescription orange-flavored cough syrup containing the active ingredient thiocol, which became a global commercial hit and established Roche's international reputation.

How did Roche pioneer mass industrial vitamin production?

In 1934, Roche became the first company in the world to mass-produce synthetic Vitamin C (under the brand name Redoxon), followed by industrial synthesis of Vitamin A, Vitamin B, and Vitamin E, becoming the dominant global vitamin supplier for decades.

What was Roche's breakthrough in psychotropic medications in the 1960s?

Chemist Leo Sternbach discovered the benzodiazepine class of tranquilizers at Roche's Nutley, New Jersey research laboratory, leading to the commercial launches of Librium (1960) and Valium (1963), the latter becoming the world's bestselling prescription drug.

When did Roche acquire Genentech and why was it historic?

Roche acquired a majority 60% stake in biotechnology pioneer Genentech in 1990 for $2.1 billion, and acquired the remaining 40% in March 2009 for $46.8 billion in one of the most successful pharmaceutical takeovers in history, transforming Roche into the world's oncology powerhouse.

What blockbuster cancer drugs did Roche acquire through Genentech?

The Genentech acquisition gave Roche exclusive global rights to historic monoclonal antibody blockbusters: Rituxan/MabThera (lymphoma), Herceptin (HER2+ breast cancer), and Avastin (angiogenesis inhibitor for colorectal/lung cancer).

How did Roche become the global leader in molecular diagnostics?

In 1991, Roche acquired the worldwide patent rights to the Polymerase Chain Reaction (PCR) technology from Cetus Corporation for $300 million, laying the foundation for modern molecular diagnostics and automated viral load testing (HIV, Hepatitis).

What happened to Roche's historical vitamin division?

In 2003, Roche divested its historic Vitamins and Fine Chemicals division to Dutch life sciences company DSM for €2.25 billion, refocusing capital exclusively on high-margin pharmaceuticals and diagnostics.

How did Roche respond to the COVID-19 pandemic?

Under then-Diagnostics CEO Thomas Schinecker, Roche rapidly developed and received FDA Emergency Use Authorization for the first commercial high-throughput molecular test (cobas SARS-CoV-2), deploying tens of millions of PCR and rapid antigen tests worldwide.

What family controls the voting shares of Roche today?

The descendants of founder Fritz Hoffmann-La Roche (the Hoffmann-Oeri-Duschmalé family pool) hold a controlling voting majority of approximately 50.1% of Roche's bearer voting shares, ensuring multi-generational strategic independence.

What major multi-billion-dollar deals did Roche execute in 2023?

In late 2023, Roche acquired Telavant for $7.1 billion (securing promising Phase 3 IBD antibody RVT-3101) and agreed to acquire Carmot Therapeutics for $2.7 billion, entering the booming anti-obesity and diabetes GLP-1/GIP drug market.

Who leads Roche as Chief Executive Officer today?

Thomas Schinecker became CEO of the Roche Group in March 2023, succeeding long-time CEO Severin Schwan, who transitioned to Chairman of the Board of Directors.

Related Companies

Compare F. Hoffmann-La Roche AG History With Competitors

Related Strategic History

Compare founding milestones and corporate evolution

Content is for informational purposes only. Not financial advice. Data sourced from SEC filings, annual reports, and public records. See our full disclaimer and methodology.