Cencora makes money on volume and services rather than markups alone. It buys medicines from manufacturers, holds them in a national network of distribution centers and delivers them, often overnight, to pharmacies, hospitals, clinics and physician offices. Revenue is enormous because the full drug price passes through its books, but adjusted gross margin is only around 4% (4.16% in the June 2026 quarter). Profit comes from distribution service fees paid by manufacturers, generic-drug sourcing, specialty distribution of oncology and other biologics, and services such as World Courier clinical-trial logistics, commercialization and market-access consulting, and management services organizations (MSOs) for retina and oncology practices.