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BioNTech SE

Founders

Who Founded BioNTech?

Prof. Ugur Sahin, M.D., Prof. Ozlem Tureci, M.D., Dr. Christoph Huber · Founded 2008 · HQ today: Mainz, Rhineland-Palatinate, Germany

Who founded BioNTech?

BioNTech was founded by Prof. Ugur Sahin, M.D., Prof. Ozlem Tureci, M.D., Dr. Christoph Huber in 2008 in Mainz, Germany. It is now led by Uğur Şahin.

Founders
Prof. Ugur Sahin, M.D., Prof. Ozlem Tureci, M.D., Dr. Christoph Huber
Founded
2008
Headquarters
Mainz, Rhineland-Palatinate, Germany
Number of founders
3
Current CEO
Uğur Şahin (since 2008)
Where was BioNTech founded?
BioNTech was founded in Mainz, Germany in 2008. wikidata.org
When was BioNTech founded?
BioNTech was founded in 2008.
Who started BioNTech?
BioNTech was founded by Prof. Ugur Sahin, M.D., Prof. Ozlem Tureci, M.D. and Dr. Christoph Huber.
How old is BioNTech?
BioNTech is 18 years old as of 2026.

Founding Story

Ugur Sahin and Özlem Türeci, both children of Turkish immigrants, met as young doctors at Saarland University Hospital in Homburg and saw standard cancer therapies fail patients whose tumors were genetically unique. While running their first company, antibody developer Ganymed (founded 2001), they founded BioNTech in 2008 with their mentor Christoph Huber and seed money from the Strüngmann twins' family office, MIG Capital and Helmut Jeggle. In late January 2020, after reading about the novel coronavirus in Wuhan, Sahin launched Project Lightspeed and redirected the mRNA platform to a vaccine. BioNTech partnered with Pfizer in March 2020, and the vaccine became the first mRNA medicine ever authorized, in the UK on December 2, 2020.

Prof. Ugur Sahin, M.D.

Co-founder 2008

Background

Ugur Sahin was born in Turkey and moved to Germany at age four, growing up in Cologne. He studied medicine at the University of Cologne, completing a doctoral thesis in cancer immunotherapy. He remained in academia as an oncohematology physician and researcher at university hospitals in Saarland and Zurich before establishing a research group at the University of Mainz in 2000 and becoming a professor of experimental oncology in 2006. In 2001, he co-founded Ganymed Pharmaceuticals with Ozlem Tureci and Christoph Huber, developing the monoclonal antibody zolbetuximab for gastrointestinal cancer. Ganymed was sold to Astellas Pharma in 2016 for over $436 million after demonstrating significant survival benefit in gastric cancer. Sahin's defining founding philosophy was the conviction that cancer treatment must be individualized because each patient's tumor is genetically unique, an insight developed through years of clinical practice watching standardized therapies fail.

Role at BioNTech SE

Ugur Sahin co-founded BioNTech in 2008 and has been its chief executive since. Born in Iskenderun, Turkey, he moved to Germany as a child, grew up in Cologne and studied medicine at the University of Cologne. He trained as a hematologist-oncologist, met Özlem Türeci at Saarland University Hospital in Homburg, and became a professor of experimental oncology at the University of Mainz. With Türeci and Christoph Huber he first founded Ganymed Pharmaceuticals in 2001, whose antibody zolbetuximab was later developed by Astellas after it bought Ganymed in 2016. At BioNTech he pushed mRNA as a way to build cancer treatments matched to each patient's tumor. In January 2020 he launched Project Lightspeed, which produced the Pfizer-BioNTech COVID-19 vaccine within the year. In March 2026 BioNTech announced that he and Türeci would leave by the end of 2026 to lead a new, separate mRNA company; Guido Oelkers succeeds him as CEO by February 1, 2027. Prof. Ugur Sahin, M.D. was born in 1965.

Background

Ozlem Tureci is a German physician and immunologist with Turkish roots who trained alongside Ugur Sahin at Saarland University Medical Center. Her clinical experience treating cancer patients directly informed BioNTech's founding mission: she witnessed firsthand how standardized therapies failed because they could not address the genetic uniqueness of each tumor. Tureci's research focus on harnessing the full potential of the immune system led her to explore multiple therapeutic modalities including antibodies, cell therapies, and mRNA, with mRNA emerging as the most advanced platform after two decades of optimization. Her defining founding philosophy was that scientific innovations must reach patients broadly, not remain trapped in academic journals, a conviction that drove the transition from university research to commercial biotechnology.

Role at BioNTech SE

Özlem Türeci is a co-founder of BioNTech and its Chief Medical Officer. A physician and immunologist born in Germany to a Turkish family, she trained at Saarland University, where she met Ugur Sahin; they married in 2002. Her clinical work with cancer patients shaped BioNTech's founding idea that tumors differ so much between patients that treatment should be tailored to each one. She co-founded Ganymed Pharmaceuticals in 2001 and BioNTech in 2008, and has led clinical development across the company's programs, from early mRNA cancer vaccine trials through the Comirnaty studies and the current oncology pipeline. She and Sahin received the German Future Prize in 2021 with Katalin Karikó and Christoph Huber. In March 2026 BioNTech announced that Türeci and Sahin would leave by the end of 2026 to run a new company developing next-generation mRNA medicines.

Dr. Christoph Huber

Co-founder 2008

Background

Christoph Huber was Ugur Sahin's mentor and scientific collaborator who co-founded Ganymed Pharmaceuticals in 2001 alongside Sahin and Tureci. At Ganymed, Huber contributed to the development of zolbetuximab, the monoclonal antibody that demonstrated significant survival benefit in gastric cancer and led to Astellas Pharma's $436+ million acquisition in 2016. Huber's scientific expertise in antibody development and translational medicine provided the technical foundation for BioNTech's early platform work, though he has maintained a lower public profile than Sahin and Tureci in the company's subsequent growth.

Role at BioNTech SE

Christoph Huber is an Austrian hematologist-oncologist and co-founder of BioNTech. As head of hematology and oncology at the University of Mainz he mentored Ugur Sahin and Özlem Türeci, and he co-founded Ganymed Pharmaceuticals with them in 2001. Ganymed developed zolbetuximab, a CLDN18.2 antibody for gastric and gastroesophageal cancers, and was acquired by Astellas Pharma in 2016. Huber brought experience in clinical immunotherapy and translational research to BioNTech's founding in 2008, helping set up its early clinical work in Mainz. He has kept a lower public profile than Sahin and Türeci, but shared the 2021 German Future Prize with them and Katalin Karikó for the work behind the mRNA COVID-19 vaccine. (Exact birth year remains publicly undisclosed).

BioNTech SE: CEO & Leadership History

Full timeline →

Guido Oelkers

Incoming Chief Executive Officer (takes office by February 1, 2027)

2027 – Present

Appointed by the Supervisory Board on August 3, 2026 to succeed Ugur Sahin. Oelkers has more than 30 years in pharma and biotech and has been CEO of Swedish Orphan Biovitrum (Sobi) since 2017. His mandate is to turn BioNTech into a multi-product oncology company by 2030.

Ramón Zapata-Gomez

Chief Financial Officer

2025 – Present

Joined from Novartis, where he was CFO of its biomedical research unit, and became CFO on July 1, 2025, succeeding Jens Holstein. He oversaw the 2026 guidance revision and the $1.0 billion ADS buyback launched in May 2026.

Sean Marett

Chief Business and Commercial Officer

2012 – 2024

Marett joined BioNTech's management in 2012 and helped negotiate its pharma partnerships, including the 2020 Pfizer collaboration on the COVID-19 vaccine. BioNTech announced his planned retirement from the Management Board in March 2024; Annemarie Hanekamp became Chief Commercial Officer on July 1, 2024.

Uğur Şahin

Chief Executive Officer and Co-Founder

2008 – Present

Sahin has led BioNTech since its 2008 founding, took it public on Nasdaq in 2019 and directed Project Lightspeed in 2020, which produced Comirnaty with Pfizer. After the pandemic he steered the company back to oncology through the Biotheus, CureVac and InstaDeep acquisitions and the 2025 Bristol Myers Squibb deal for pumitamig. He leaves by the end of 2026 to lead a new mRNA company with Özlem Türeci.

Özlem Türeci

Chief Medical Officer and Co-Founder

2008 – Present

Türeci has run BioNTech's clinical development since 2008, from early mRNA cancer vaccine trials to Comirnaty and the late-stage oncology portfolio. She leaves with Sahin by the end of 2026.

Keep researching BioNTech

Who Founded BioNTech? FAQ

Who founded BioNTech and in what year was it incorporated?

BioNTech was founded in 2008 in Mainz, Germany, by Prof. Ugur Sahin, Prof. Özlem Türeci and Prof. Christoph Huber, with seed funding from the Strüngmann family office, MIG Capital and Helmut Jeggle.

Who provided BioNTech's seed financing?

BioNTech's seed round of about $203 million (€180 million) came from the family office of twins Thomas and Andreas Strüngmann, who had founded generics maker Hexal, together with MIG Capital and Helmut Jeggle. The Strüngmanns' AT Impf GmbH remains the largest shareholder.

What scientific problem did the founders set out to solve in 2008?

The founders recognized that every patient's cancer tumor contains a unique set of genetic mutations (neoantigens). They set out to build mRNA technology that could be custom-tailored to instruct the patient's own immune system to target these specific unique mutations.

How did the founders work with Katalin Karikó on mRNA technology?

In 2013, the founders recruited Dr. Katalin Karikó (2023 Nobel Laureate in Physiology or Medicine) to BioNTech as Senior Vice President of RNA Protein Replacement, integrating her groundbreaking discoveries on modified nucleosides (pseudouridine) to eliminate toxic immune reactions to therapeutic mRNA.

What was TRON and how did the founders establish it?

In 2010, the founders established TRON (Translational Oncology at the Medical Center of the Johannes Gutenberg University Mainz), a non-profit biopharmaceutical research institute that conducts basic science and translational genomics feeding into BioNTech's clinical pipeline.

When did BioNTech complete its US Initial Public Offering (IPO)?

BioNTech completed its US IPO on the NASDAQ in October 2019, raising $150 million at a valuation of approximately $3.4 billion, just three months before the emergence of the novel coronavirus that sparked Project Lightspeed.

What personal background shaped the dedication of founders Şahin and Türeci?

Both children of Turkish immigrants to Germany, Şahin and Türeci met while working at Homburg University Hospital. Driven by their daily clinical experiences treating terminal cancer patients, they even spent part of their 2002 wedding day in the laboratory conducting research.

What legacy have the BioNTech founders established in modern medicine?

The founders validated synthetic mRNA as a brand-new class of therapeutic medicine, breaking global records for vaccine development speed and paving the way for a new era of individualized genetic and immunological therapies.

Who founded BioNTech?

The company was founded by the husband-and-wife team of Uğur Şahin and Özlem Türeci (both physicians of Turkish descent), along with Austrian oncologist Christoph Huber.

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