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Bristol-Myers Squibb vs TotalEnergies: Revenue, Profit and Business Model

Bristol-Myers Squibb reported $48.2B of revenue in FY2025 and $7.1B of net income. TotalEnergies reported $201.2B of revenue in FY2025 and $13.1B of net income.

Latest financial snapshot

Bristol-Myers Squibb

Latest revenue
$48.2B (FY2025)
Net income
$7.1B
Net margin
14.6%
Revenue growth
+10.6% a year, FY2016–FY2025

TotalEnergies

Latest revenue
$201.2B (FY2025)
Net income
$13.1B
Net margin
6.5%
Revenue growth
+5.2% a year, FY2016–FY2025

Financial summary

Bristol-Myers Squibb

Revenue grew from $19.4 billion in 2016 to $42.5 billion in 2020 as Celgene's sales were added, and has stayed between $45.0 billion and $48.3 billion since 2021. Net earnings are far less stable because BMS expenses acquired in-process R&D: the $11.4 billion MyoKardia charge produced a $9.0 billion net loss in 2020, and the Karuna charge produced an $8.9 billion loss in 2024. Cash generation is steadier, with free cash flow of about $12.8 billion in 2025. That cash funds a dividend raised for a 17th straight year in February 2026, to $0.63 a quarter, and debt reduction, from $51.2 billion at the end of 2024 to $47.2 billion a year later. On July 30, 2026 BMS raised its 2026 revenue guidance to $49.0 to $50.0 billion, from $46.0 to $47.5 billion, after second-quarter revenue rose 6 percent to $12.97 billion.

TotalEnergies

TotalEnergies' 2025 results showed how much its earnings still track oil prices. Revenues from sales fell to $182.344 billion (total revenues including excise taxes of $201.2 billion), adjusted net income dropped 15% to $15.6 billion and IFRS net income attributable to shareholders was $13.1 billion. Cash flow slipped only 7% to nearly $28 billion because upstream production grew about 4%. Gearing ended 2025 at 15%, ROACE was 12.6% and the 2025 dividend rose 5.6% to €3.40 per share. In 2026, higher crude prices linked to the Middle East conflict reversed the trend: second-quarter adjusted net income reached $6.0 billion, cash flow $9.8 billion and first-half adjusted net income about $11.4 billion.

Revenue and profit by year

Bristol-Myers Squibb

Bristol-Myers Squibb revenue, net income, margin and growth by fiscal year
YearRevenueNet incomeMarginGrowthSource
FY2025$48.2B$7.1B14.6%-0.2%Source
FY2024$48.3B-$8.9B-18.5%+7.3%Source
FY2023$45B$8B17.8%-2.5%Source
FY2022$46.2B$6.3B13.7%-0.5%Source
FY2021$46.4B$7B15.1%+9.1%Source
FY2020$42.5B-$9B-21.2%+62.6%Source
FY2019$26.1B$3.4B13.2%+15.9%Source
FY2018$22.6B$4.9B21.8%+8.6%Source
FY2017$20.8B$1B4.8%+6.9%Source
FY2016$19.4B$4.5B22.9%—Source
Full Bristol-Myers Squibb financials

TotalEnergies

TotalEnergies revenue, net income, margin and growth by fiscal year
YearRevenueNet incomeMarginGrowthSource
FY2025$201.2B$13.1B6.5%-6.2%Source
FY2024$214.6B$15.8B7.3%-9.5%Source
FY2023$237.1B$21.4B9.0%-15.6%Source
FY2022$281B$20.5B7.3%+36.5%Source
FY2021$205.9B$16B7.8%+46.3%Source
FY2020$140.7B-$7.2B-5.1%-29.8%Source
FY2019$200.3B$11.3B5.6%-4.3%Source
FY2018$209.4B$11.4B5.5%+40.4%Source
FY2017$149.1B$8.6B5.8%+16.6%Source
FY2016$127.9B$6.2B4.8%—Source
Full TotalEnergies financials

Where the revenue comes from

Bristol-Myers Squibb

  • Growth Portfolio~55%

    $26.4 billion in 2025, up 17%: Opdivo, Opdivo Qvantig, Orencia, Yervoy, Reblozyl, Breyanzi, Opdualag, Camzyos, Sotyktu, Cobenfy, Krazati and other newer brands. It grew another 15% to $7.56 billion in the second quarter of 2026.

  • Legacy Portfolio~45%

    $21.8 billion in 2025: Eliquis ($14.4 billion), Revlimid ($3.0 billion), Pomalyst/Imnovid ($2.7 billion), Sprycel, Abraxane and other mature brands facing generic competition. Legacy revenue fell 4% in the second quarter of 2026.

TotalEnergies

  • Exploration & Production

    Not disclosed here

    Sales of crude oil and gas from about 2.5 million boe per day of 2025 production.

  • Integrated LNG

    Not disclosed here

    Liquefaction, shipping, trading and sale of LNG and gas under long-term and spot contracts.

  • Integrated Power

    Not disclosed here

    Wholesale and retail electricity from renewables, gas-fired plants and storage, plus retail gas supply.

  • Refining & Chemicals

    Not disclosed here

    Refined fuels, polymers and petrochemicals from integrated industrial platforms.

  • Marketing & Services

    Not disclosed here

    Retail and B2B sales of fuels, lubricants, aviation fuel and EV charging.

Business model and strategy

Bristol-Myers Squibb

How it makes money

BMS discovers, licenses or buys drug candidates, takes them through clinical trials, and sells approved medicines under patent protection to wholesalers, specialty pharmacies and hospitals. Net product sales were $46.8 billion of the $48.2 billion total in 2025; alliance, royalty and other revenues made up the remaining $1.4 billion, including royalties from Merck on Winrevair.

Growth strategy

BMS is pursuing growth on three fronts. First, scaling the Growth Portfolio (Opdivo Qvantig, Reblozyl, Camzyos, Breyanzi, Opdualag, Cobenfy and others), which rose 17 percent to $26.4 billion in 2025 and 15 percent to $7.56 billion in the second quarter of 2026.

Competitive advantage

BMS's advantage is its expertise in oncology and its large commercial and regulatory organization. Developing a cancer immunotherapy is complex, and winning approval from regulators and getting doctors to prescribe it requires an established global sales and regulatory team.

Bristol-Myers Squibb business model in full

TotalEnergies

How it makes money

TotalEnergies makes money across five reporting segments. Exploration & Production sells crude oil and gas from about 2.5 million barrels of oil equivalent per day of output. Integrated LNG liquefies, ships, trades and sells gas from projects in Qatar, the U.S., Nigeria, Australia, Papua New Guinea and elsewhere.

Growth strategy

TotalEnergies' strategy centers on low-cost oil and gas production, LNG integration, disciplined downstream operations, renewable power capacity, electricity customers, and cash returns to shareholders.

Competitive advantage

TotalEnergies has an integrated LNG platform, upstream assets across multiple basins, downstream and marketing positions, and a growing power portfolio. Its advantage is breadth across molecules, refined products, and electrons.

TotalEnergies business model in full

Questions about Bristol-Myers Squibb vs TotalEnergies

Which company has higher revenue — Bristol-Myers Squibb Company or TotalEnergies SE?

Bristol-Myers Squibb Company reported $48.2B (FY2025), while TotalEnergies SE reported $201.2B (FY2025). By last reported revenue, TotalEnergies SE is the larger business, with Bristol-Myers Squibb Company reporting a smaller revenue base.

What is the market cap of Bristol-Myers Squibb Company vs TotalEnergies SE?

Bristol-Myers Squibb Company's market capitalisation stands at $127.5B, while TotalEnergies SE's is $205.0B. TotalEnergies SE carries the higher market valuation, reflecting investors' expectations of its future earnings power relative to Bristol-Myers Squibb Company.

Which is more financially efficient — Bristol-Myers Squibb Company or TotalEnergies SE?

Bristol-Myers Squibb Company generates $1.48M / employee in revenue per employee, while TotalEnergies SE generates $2.01M / employee. TotalEnergies SE shows higher revenue efficiency per headcount, though this reflects business model differences — capital-light software companies routinely outperform labour-intensive manufacturers on this metric.

How do Bristol-Myers Squibb Company and TotalEnergies SE make money?

Bristol-Myers Squibb Company and TotalEnergies SE generate revenue in fundamentally different ways. Bristol-Myers Squibb Company: BMS discovers, licenses or buys drug candidates, takes them through clinical trials, and sells approved medicines under patent protection to wholesalers, specialty pharmacies and hospitals. TotalEnergies SE: TotalEnergies makes money across five reporting segments.

Which company is valued higher relative to revenue — Bristol-Myers Squibb Company or TotalEnergies SE?

On a price-to-sales (P/S) basis, Bristol-Myers Squibb Company trades at 2.6x P/S and TotalEnergies SE at 1.0x P/S. Bristol-Myers Squibb Company commands a higher revenue multiple, typically indicating that investors expect faster growth or higher future margins compared to TotalEnergies SE. A higher multiple is not inherently better — it may also signal that the stock is priced for perfection.

Is Bristol-Myers Squibb Company bigger than TotalEnergies SE?

By last reported revenue, TotalEnergies SE ($201.2B (FY2025)) is the larger company compared to Bristol-Myers Squibb Company ($48.2B (FY2025)). Revenue scale is one dimension of size — market capitalisation, employee count, and geographic reach are also relevant depending on the context.

Figures come from each company's filings and the sources linked beside them. Amounts reported in another currency are shown in US dollars at an approximate rate and marked with ~. Back to the Bristol-Myers Squibb vs TotalEnergies overview

Content is for informational purposes only. Not financial advice. Data sourced from SEC filings, annual reports, and public records. See our full disclaimer and methodology.